Fly (Drosophila) Facility
The availability of the complete annotated sequence of the Drosophila genome coupled with the invention of a number of elegant genetic techniques has made the fruit fly a more attractive model system than ever before. The NCBS-fly facility managed by Centre for Cellular and Molecular Platforms (C-CAMP) offers a world class microinjection service for the generation of transgenic lines, Screening Platforms, Drosophila strain development and also, maintains a large number of mutant strains and transgenic lines.
Drosophila embryo injection work for transgenic production is a labour intensive process and requires technical expertise. This process often diverts attention from the core research project. We are offering Drosophila Transgenesis services at competitive prices. We have range of services from DNA preparation, embryo injection, selection of transformants, mapping the insertions to balancing the insertions. With the state-of-art equipment and the experienced staff we are able to generate transgenics in high-throughput rate. The highly motivated team has successfully generated 5000 transgenics for a collaborative project and few hundreds of transgenics for others.
Currently we are offering following service plans:
Submitting a Drosophila Transgenic Service request:
To submit a request for Drosophila Transgenic services, please register by clicking here. After registration, please login and click on "My requests" in the menu bar followed by "New request".
The desired service form (P-element or Site-specific) can be filled and submitted to us.
Registered users can submit a service request by clicking here.
Screening arm of fly facility is open to Drosophila research groups to use RNAi, TILLING and chemical compound libraries to screen candidates for any gene of interest. Such requests can be taken up under collaboration.
Developing a new strain (genotype) or a recombinant by crossing two or more fly lines and submitting stable lines to the clients.
With the state-of-the-art facility, we offer Drosophila stock maintenance services. A dedicated team of stock keepers under the guidance of skilled Fly Stock Curator maintains the fly stocks with high standards of fly husbandry.
Achievements and Collaborations
Highly skilled team at our fly facility has generated >5000 transgenics for DPiM(Drosophila Protein interaction Map) a collaborative project with Harvard Medical School, Boston, USA.
We have successfully generated transgenics for BAC clones of size ranging from 35kb to >80kb size.
Currently we are involved in generating transgenics for the project TransgeneOme in collaboration with MPI-CBG, Dresden, Germany.
Some of our esteemed customers
Vinay Vikas K.J
Email: services[at]ccamp.res.in or tff[at]ncbs.res.in
Phone: +91-80-2366 6231/2