In the year 2009-10, Dept. of Biotechnology (DBT), Ministry of Science & Technology, Govt. of India, mandated C-CAMP to establish a state-of-art Biologics Characterization Facility to exclusively cater to the Indian BioPharma Industry, comprising of established companies, SMEs and Startups desirous of taking up Biologics/Biosimilar development work.
Biopharmaceuticals can exhibit tremendous heterogeneity in terms of posttranslational modifications (PTMs) such as glycosylation, oxidation, deamidation, phosphorylation etc. and structural modifications. In addition to this, changes in upstream and downstream processes during recombinant production of biologics also influence structural heterogeneity. Therefore, comprehensive characterization of biologics is necessary to ensure safety and efficacy.
We are working towards making the Biologics Characterization Facility compliant to GLP standards.