Libraries

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CHEMICAL and GENOMIC LIBRARIES

- Drosophila RNAi Library 2.0, RDM4220 (Open Biosystems)

The Drosophila RNAi Library-dsRNA templates is a collection of over 15,000 dsDNA templates provided in 96 well PCR plates, ready for in vitro transcription (IVT) to dsRNA constructs that target the entire Drosophila genome. dsDNA templates were generated using gene specific primers to amplify 200-800 bases of exonic sequence for each gene. Individual dsRNAs can be cherry picked from the library and transcribed readily on request.

- HUMAN pGIPZ  LENTIVIRAL shRNAmir Library Cat No: RHS5828 (Thermo Scientific/Open Biosystems)

The Thermo Scientific Open Biosystems GIPZ Lentiviral shRNAmir Library was developed in collaboration with Dr. Greg Hannon (CSHL) and Dr. Steve Elledge (Harvard). This library combines the design advantages of microRNA-adapted shRNA (shRNAmir) with the pGIPZ lentiviral vector to create a powerful RNAi trigger capable of producing RNAi in most cell types including primary and non-dividing cells.

- Dundeee Library

Dundee library is a collection of 18000 structurally diverse scaffolds which is intended to be used for infective diseases

- MMV library

The Malaria Box has been assembled by MMV in a bid to catalyse malaria and neglected disease drug discovery and research. All of the compounds have confirmed activity against the blood-stage of P. falciparum and are commercially available. It includes:

  • 200 diverse drug-like compounds as starting points for oral drug discovery and development
  • 200 diverse probe-like compounds for use as biological tools in malaria research