Listed below are the Publications supported by Technology platforms at C-CAMP / Bangalore Life Science Cluster.
Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors. Bioorganic & Medicinal Chemistry. 26:25-36.. 2018.
Identification and characterization of a calcium dependent bacillopeptidase from Bacillus subtilis CFR5 with novel kunitz trypsin inhibitor degradation activity. [Mass Spectrometry Facility - Proteomics]. Food Res Int. 103:263-272.. 2018.
Tailor-made ezrin actin binding domain to probe its interaction with actin in-vitro. [Protein Technology Core]. PLoS One. 10(4):e0123428.. 2015.
Molecular mechanism of interactions between Chrysin and I-kappa-B kinase epsilon (IKKe)/Tank Binding Kinase-1(TBK1): Cell based assay and insilico molecular docking studies [High Throughput Screening Facility].. J Biomol Struct Dyn. :1-9.. 2019.
Highly Sensitive LC-MS/MS-ESI method Development for the Determination of 5,7-dihydroxyflavone in Mouse Plasma and Pharmacokinetic Study in Lean and Diet Induced Obese Mice [High Throughput Screening Facility].. Der Pharmacia Lettre. 10(11). 2018.
A Naturally Occurring Flavone (Chrysin): Chemistry, Occurrence, Pharmacokinetic, Toxicity, Molecular Targets and Medicinal Properties [High Throughput Screening Facility].. Journal of Biologically Active Products from Nature. 8:208-227.. 2018.
Draft Genome Sequence of Acinetobacter baumannii Strain MSP4-16. (Next Generation Genomics). Genome Announc. 1(2):e0013713.. 2013.
Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway [Discovery to Innovation Accelerator]. Nat Commun. 10(1):89.. 2019.
Development of the structural core and of conformational heterogeneity during the conversion of oligomers of the mouse prion protein to worm-like amyloid fibrils.. J Mol Biol. 423(2):217-31.. 2012.
Small molecule modulator of aggrephagy regulates neuroinflammation to curb pathogenesis of neurodegeneration [Discovery to Innovation Accelerator].. EBioMedicine.. 2019.
Gene expression is implicated in the ability of pikas to occupy Himalayan elevational gradient. [Next Gen Genomics Facility]. PLoS One. 13(12):e0207936.. 2018.
Transcriptomics analysis of propiconazole-treated Cochliobolus sativus reveals new putative azole targets in the plant pathogen [Next Gen Genomics Facility].. Funct Integr Genomics.. 2019.
Targeted, Site-specific quantitation of N- and O-glycopeptides using (18)O-labeling and product ion based mass spectrometry.. Glycoconj J. 34(1):95-105.. 2017.
Genomic analysis reveals epistatic silencing of "expensive" genes in Escherichia coli K-12. [Next Generation Genomics facility]. Mol Biosyst. 9(8):2021-33.. 2013.
An inhibitor of nonhomologous end-joining abrogates double-strand break repair and impedes cancer progression.. Cell. 151(7):1474-87.. 2012.
Identification of multiple isomeric core chitobiose-modified high-mannose and paucimannose -glycans in the planarian. [Mass Spectrometry Facility - Glycomics]. J Biol Chem. 293(18):6707-6720.. 2018.
Nickel azamacrocyclic complex activated persulphate based oxidative degradation of methyl orange: recovery and reuse of complex using adsorbents [Mass spectrometry - Metabolomics]. RSC Adv.. 5:31716-31724.. 2015.
Generation of Transplantable Retinal Pigmented Epithelial (RPE) Cells for Treatment of Age-Related Macular Degeneration (AMD). [Eyestem, a C-CAMP Startup]. Methods Mol Biol.. 2018.
Differentiating Human Induced Pluripotent Stem Cells (iPSCs) Into Lung Epithelial Cells. [Eyestem, a C-CAMP Startup]. Curr Protoc Stem Cell Biol. :e86.. 2019.
Mechanism of apoptosis induction in human breast cancer MCF-7 cell by Ruviprase, a small peptide from Daboia russelii russelii venom.[Mass Spectrometry]. Chem Biol Interact. 258:297-304.. 2016.
Biochemical and pharmacological characterization of a toxic fraction and its cytotoxin-like component isolated from Russell's viper (Daboia russelii russelii) venom. (Mass Spectrometry). Comp Biochem Physiol C Toxicol Pharmacol. 168:55-65.. 2015.
Elucidation of procoagulant mechanism and pathophysiological significance of a new prothrombin activating metalloprotease purified from Daboia russelii russelii venom. (Mass Spectrometry). Toxicon. 100:1-12.. 2015.
Microscopic elucidation of abundant endophytic bacteria colonizing the cell wall–plasma membrane peri-space in the shoot-tip tissue of banana. Oxford Journal AoB PLANTS (2013) 5 : plt011.. 2013.
Prevention of pesticide-induced neuronal dysfunction and mortality with nucleophilic poly-Oxime topical gel. [BIG Grant Supported Entrepreneur]. Sci Adv. 4(10):eaau1780.. 2018.