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Method of Determining Effect of Anti-Obesity Molecule

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The Novel Technology:

The invention discloses a method of determining the anti-obesity effect of a molecule, using mutant Drosophila strains. Moreover, the invention is useful for testing drugs developed to reduce appetite, reduce fatty acid uptake from the intestine and reduce excess fat deposits. 
 
Applications:
  • To test for drugs that reduces excess triglyceride deposits by:
  • Altering lipid absorption in the intestine and its effects on fat storage tissues
  • Altering appetite levels and in turn reduction of weight
Advantages:
  • Very cost-efficient means for initial testing of drugs
  • Allows for testing toxicity levels of the drug simultaneously by measuring other parameters like activity of the animals post drug ingestion
  • Comparable with human conditions of genetic tendency for weight gain with a normal diet
Business Model:
The technology is at early-stage of development. Initial studies have been done using the anti-obesity compounds available in the market. Technology know-how is available and looking for partners to further develop and commercialize the technology. 
 
Principal Investigator(s): Dr. Gaiti Hasan, NCBS
 
Invention ID: CMP-016
 
IP Status: Patent Abandoned
 
Jurisdictions: All
 
For more details, please write to:
techtransfer @ ccamp.res.in